Fragment/ Small Molecule Screening 

NMR screening methods of fragments/small molecules allow for concurrent hit identification, binding confirmation, binding site location and binding affinity determination. Additionally, automated screening processes allow for accurate and rapid data collection and analysis.

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• Our modern methods and cutting edge technology allow for the lowest sample concentrations and fastest turnaround times in the industry.

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• The advantage is a faster turnaround time at an economical cost that we pass on to our partners.

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• Ligand-observe methods (STD/waterLOGSY/CPMG)

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• Target observe methods (2D HSQC/HMQC)

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• Competition assays

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• Binding constant determination (Kd)

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• Screening of external libraries

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• Library Smart pooling capabilities

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• Pre-screen Library QC 

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• Pre-screen Target QC and stability analysis